Ann M. Stowe
Ann M. Stowe, Ph.D., is an Associate Professor with Tenure in the Dept. of Neurology at the University of Kentucky (Lexington, KY, USA). My overarching hypothesis is that the adaptive immune system – driven by an autoreactivity to CNS-derived antigens – plays a fundamental role in functional plasticity and subsequent motor and cognitive recovery within the injured brain. Although she use preclinical studies to investigate the mechanisms by which adaptive immune responses affect post-stroke plasticity, it is critical to concomitantly confirm and characterize these cells in humans. Her clinical studies into the role of neuroinflammation during brain injury and repair has expanded beyond the field of ischemic stroke to also include subjects with amnestic mild cognitive impairment and pediatric patients on ventilator and hemodynamic support who experience stroke. The combination of preclinical and clinical studies reflects both my own training, which included a clinical postdoctoral fellowship, and my ongoing scientific philosophy that translational research will hasten the collective understanding of functional recovery during and following brain injury. It is in the capacity of a clinical researcher that she have become Co-Founder and equity holder of Cerelux, LLC.